The organization started as a Community based Organization (CBO) known as Kimilili Integrated Development Education Programme (KIDEP) in 1993. In 2006 the organization transformed itself into a registered Non-Governmental Organization (NGO) named DESECE, because there was a need to cover an expanded needy population of 2,406,528 people with a population density of about 318 persons per square kilometre in the region. The organization was based in Misikhu in a rented premise till 2012. Then the organization managed to purchase a piece of land in Mukuyuni and later constructed new offices with the support of international partners to serve the needs of the beneficiaries, stakeholders and the organization.
DESECE now carries out development programs in Bungoma, parts of Kakamega and Trans-Nzoia Counties, with a focus on awareness creation using Training for Transformation as a methodology, peace and reconciliation, civic education including human rights, leadership trainings, gender, HIV and Aids, sustainable organic agriculture, ERI (Enabling Rural Innovation) and environmental management. The programs aim at motivating and empowering the target population to take active responsibilities of transforming their own life situations and facilitate their own development processes by setting their own goals and organizing for action to address their development needs.